In a small study, a bivalent mRNA vaccine targeting omicron BA.4-BA.5 sublineages resulted in similar neutralization of other SARS-CoV-2 variants as a fourth dose of a monovalent mRNA vaccine.. Pfizer Inc. (NYSE: PFE) and BioNTech SE (Nasdaq: BNTX) today announced that the U.S. Food and Drug Administration (FDA) granted Emergency Use Authorization (EUA) for a 10-µg booster dose of their Omicron BA.4/BA.5-adapted bivalent COVID-19 vaccine in children 5 through 11 years of age. Pending recommendation from the Centers for Disease Control and Prevention (CDC), 10-µg doses will be.
FDA authorizes bivalent COVID19 boosters for children ages 5 to 11
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Pfizer’s new BA.4/5 bivalent vaccine differs from its previous formulation by replacing mRNA of the BA.1 Omicron subvariant with mRNA that encodes the BA.4/5 spike protein instead.. However, the eligibility criteria shared by the Department suggest that individuals aged 18 and over can choose either of the four bivalents: Pfizer BA.1, Moderna BA.1, Pfizer BA.4/5, and Moderna.
